CAN_419 |
| origin: |
Elucidation of the molecular mechanisms of two nanobodies that inhibit thrombin-activatable fibrinolysis inhibitor activation and activated thrombin-activatable fibrinolysis inhibitor activity. |
| author: |
Zhou, X., Weeks, S.D., Ameloot, P., Callewaert, N., Strelkov, S.V., Declerck, P.J. |
| patent: |
no |
| patent_application_number: |
null |
| CDR1_seq: |
null |
| CDR1_length: |
|
| CDR2_seq: |
null |
| CDR2_length: |
|
| CDR3_seq: |
null |
| CDR3_lentgh: |
|
| protein_seq: |
QVQLQESGGGLVQAGGSLRLSCAASGSIFSPNAMGWYRQAPGKERELVAARTNVGSTYADSVKGRFTVSRDNAKNTVYLQ
MNSLKPEDTAVYYCNAWGQDGWLGQYDYWGQGTQVTVSSHHHHHH
|
| DNA_seq: |
null |
| PubMed_ID: |
27279497 |
| PDB_ID: |
5HVF |
| PDB_deposition_date: |
2016-01-05 |
| PDB_released_date: |
2016-06-01 |
| resolution: |
2.85Ã… |
| source_organism: |
Vicugna pacos |
| experiment_method: |
null |
| antigen: |
Thrombin-activatable fibrinolysis inhibitor (TAFI) |
| antigen_chain: |
null |
| antigen_seq: |
null |
| function: |
profibrinolytic therapeutics |
| validationORprediction: |
Experimentally Validated |
| epitope: |
null |
| bacteria_family: |
null |
| publication: |
J Thromb Haemost. 2016 Aug;14(8):1629-38. doi: 10.1111/jth.13381. Epub 2016 Jul 27. |
